Dzjemma Sarkisjan Selected Research

fluorocyclopentenylcytosine

4/2020	RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.
4/2019	RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
1/2018	DNA methyltransferases expression in normal tissues and various human cancer cell lines, xenografts and tumors.
12/2016	The radiosensitizing effect of fluorocyclopentenyl-cytosine (RX-3117) in ovarian and lung cancer cell lines.
1/2016	The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.
12/2013	Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360).

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Dzjemma Sarkisjan Research Topics

Disease

6	Neoplasms (Cancer) 04/2019 - 12/2013
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2020 - 12/2016
2	Lung Neoplasms (Lung Cancer) 12/2016 - 12/2016
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2018
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018
1	Leukemia 12/2016
1	Ovarian Neoplasms (Ovarian Cancer) 12/2016

Drug/Important Bio-Agent (IBA)

6	fluorocyclopentenylcytosineIBA 04/2020 - 12/2013
4	DNA (Deoxyribonucleic Acid)IBA 04/2020 - 12/2016
3	Proteins (Proteins, Gene)FDA Link 04/2020 - 01/2018
3	CytosineIBA 04/2020 - 12/2016
3	MethyltransferasesIBA 04/2019 - 01/2018
3	Gemcitabine FDA Link 04/2019 - 12/2013
2	AntimetabolitesIBA 04/2019 - 01/2018
2	CytidineIBA 12/2016 - 12/2013
1	Cadherins (E-Cadherin)IBA 04/2020
1	Uridine KinaseIBA 04/2019
1	EnzymesIBA 04/2019
1	Biomarkers (Surrogate Marker)IBA 04/2019
1	Cytidine DeaminaseIBA 04/2019
1	PlasticsIBA 01/2019
1	EpitopesIBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2018
1	Cell Cycle ProteinsIBA 12/2016
1	Radiation-Sensitizing AgentsIBA 12/2016
1	DeoxyuridineIBA 12/2016

Therapy/Procedure

1	Therapeutics 01/2019